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    1 year ago

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    When any living organism wishes to break down a larger compound – whether a string of DNA, or a complex sugar, or plastic – they turn to enzymes, tiny molecular machines within a cell, specialised for that task.

    Enzymes work by helping chemical reactions happen at a microscopic scale, sometimes forcing reactive atoms closer together to bind them, or twisting complex molecules at specific points to make them weaker and more likely to break apart.

    For most of the roughly 200 years we have been seriously studying them, microbes were in a sort of scientific jail: mainly assumed to be pathogens in need of eradication, or simple workhorses for a few basic industrial processes, such as fermenting wine or cheese.

    About 25 years ago, the consensus among scientists was that there were probably fewer than ten million species of microbes on the planet; in the past decade, some new studies have put the number as high as a trillion, the vast majority still unknown.

    A recent critical review in the journal Nature noted that many kinds of plastics would probably never be efficiently enzymatically digested, because of the comparatively huge amount of energy required to break their chemical bonds.

    “There is not exactly a market incentive to clean up our waste, whether it’s CO2, or plastic,” says Victor di Lorenzo, a scientist at the Spanish National Biotechnology Centre in Madrid, and an evangelist for the large-scale application of microbes to solve humanity’s problems.


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